APOTHE
TulipRx PDRN Retinal Night Cell Ampoule
TulipRx PDRN Retinal Night Cell Ampoule
14 mL
Good to know
- Anti-aging
- Korean
- Korean skincare
- Niacinamide
- Not for pregnant
- Panthenol
- Pdrn
- Serum
Details
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- Fine lines
- Smoother texture
- PM only
How to use
PM
- Use in the evening only.
- After cleansing, apply 2–3 drops to dry face and neck, avoiding eyes and lips.
- Follow with a moisturiser.
- Start 2–3 evenings a week and increase slowly.
- Always use sunscreen during the day.
Who it is suited for
- Fine lines, rough texture and enlarged-looking pores.
- Uneven or sun-aged skin.
- Skin that already tolerates retinol, or a careful start 2–3 evenings a week. Not during pregnancy.
Key ingredients
RETINAL (RETINALDEHYDE)
A fast-acting form of vitamin A. Helps smooth fine lines and refine texture with regular use over months.
PDRN
A DNA-based ingredient popular in Korean skincare, used for a calm, supple skin feel.
TULIPRX™ COMPLEX
The brand's tulip extract complex, for a soothing skin feel.
INCI
Water, Glycerin, Dipropylene Glycol, Panthenol, Isododecane, 1,2-Hexanediol, Glycereth-26, Niacinamide, C12-15 Alkyl Benzoate, Polyglyceryl-3 Distearate, Ectoin, Butylene Glycol, Diethoxyethyl Succinate, Macadamia Seed Oil, Squalane, Isopropyl Myristate, Caprylic/Capric Triglyceride, Hydroxypropyl Cyclodextrin, Hydrogenated Lecithin, Glyceryl Stearate, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Ammonium Acryloyldimethyltaurate/VP Copolymer, Ethylhexylglycerin, Tromethamine, Cholesterol, Polyglyceryl-10 Laurate, Glyceryl Stearate Citrate, Brassica Campestris (Rapeseed) Sterols, Silica, Xanthan Gum, Polyglyceryl-3 Methylglucose Distearate, Retinal, Adenosine, Tocopherol, Aluminum/Magnesium Hydroxide Stearate, Disodium EDTA, Sucrose Distearate, Potassium Cetyl Phosphate, Pentaerythrityl Tetra-di-t-butyl Hydroxyhydrocinnamate, Hydrolyzed Sodium Hyaluronate, Centella Asiatica Extract, Fig Extract, Lactococcus Ferment Lysate, Ceramide NP, Fructooligosaccharides, Cyperus Rotundus Root Extract, Black Soybean Extract, Sodium DNA, Black Rice Extract, Hydrolyzed Collagen, Acai Palm Fruit Extract, Black Ginseng Extract, Sodium Chloride, Beta-Sitosterol, Phytosterols
Ingredient list for the reviewed formula. Formulas can change; check the ingredient list on your packaging, especially if you have an allergy.
Apothe TulipRx PDRN Retinal Night Cell Ampoule is a Korean night ampoule with retinal, a fast-acting form of vitamin A, combined with PDRN and a tulip extract complex. I suggest it for fine lines, rough texture, enlarged-looking pores and an uneven tone, if you already know retinol or would like a small, concentrated bottle for the evening.
Retinal (retinaldehyde) is one step closer than retinol to retinoic acid, the form the skin actually uses, so it usually works a little faster and can also irritate a little more. The small 14 ml bottle is used drop by drop. Apothe does not publish the retinal percentage. In the ingredient list, retinal comes after the thickeners, which fits the low amounts in which retinal is normally used. The formula also contains panthenol, niacinamide and ectoin to support the skin barrier. You can find the full list in the ingredients section. Start slowly, two to three evenings a week, and always wear sunscreen during the day.
🔬 Does vitamin A skincare really work on fine lines?
In a one-year double-blind study, 62 adults used either a cream with 0.1% stabilised retinol or the same cream without retinol on the whole face. The retinol group improved more than the comparison group at every check-up, and after 52 weeks fine lines around the eyes had improved by 44% and blotchy pigmentation by 84%.1 To be honest, the evidence is weaker than these numbers suggest: the study tested retinol, not retinal, in a different cream, and a 2021 review of nine such retinol trials found that almost all were paid for by the product makers and that the overall proof is weak.2 Retinal works on the same pathway, so I see this ampoule as a realistic long-term helper that needs months of regular use, always with daily sunscreen.
1. Randhawa M, Rossetti D, Leyden JJ, et al. One-year topical stabilized retinol treatment improves photodamaged skin in a double-blind, vehicle-controlled trial. J Drugs Dermatol. 2015;14(3):271–276.
2. Spierings NMK. Evidence for the efficacy of over-the-counter vitamin A cosmetic products in the improvement of facial skin aging: a systematic review. J Clin Aesthet Dermatol. 2021;14(9):33–40.
Questions about Apothe TulipRx PDRN Retinal Night Cell Ampoule
Can I use it during pregnancy?
No. It contains retinal, a form of vitamin A. I recommend avoiding retinoid skincare during pregnancy.
How do I start?
Two to three evenings a week: 2–3 drops on dry skin after cleansing, then moisturiser. If your skin stays calm for two weeks, increase slowly. Some dryness or flaking in the first weeks is normal; redness and burning are a sign to slow down.
Can I combine it with vitamin C or acids?
Not in the same routine. Use vitamin C in the morning and this ampoule in the evening, and skip exfoliating acids on retinal nights.
For a gentler start, have a look at the ISNTREE Hyper Retinol EX 1.0 Serum, see my full retinol & retinal selection, or all anti-aging skincare.
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